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Syria's Bashar Al-Assad faces a difficult tightrope walk as allies in the region, such as Hassan Nasrallah, are taken out by Israel in quick succession.
Syrians will also be awaiting the 5 November elections to see which leader enters the White House, but few experts expect major changes to US-Syria policy.
As US influence wanes in the Middle East, Riyadh's steps towards normalisation must be considered within the wider context of prioritising regional stability and economic cooperation above rivalry and conflict.
As Iraq marks 20 years since the US invasion, the effects continue to be felt in the political instability, corruption, and sectarian violence plaguing the country.
Syria has witnessed another year of extreme suffering in 2022, with the next 12 months expected to get worse for other reasons. We spell out the three key issues that will affect Syrians in 2023.
A recent conflict between former Syrian rebels and a suspected Islamic State group cell has highlighted the growing instability in Daraa province. Will the destruction of this IS cell make the southern Syrian province safer?
Movements in the US Congress could see action against the Assad regime's captagon trade, but after years of negligence could it be too late?
Northeast Syria remains one of the worst-hit areas of the country by the latest cholera outbreak, which threatens thousands of lives.
What are the reasons behind Arab countries sudden normalisation of the Assad regime, after years of isolation?
Whilst the main protagonists of the Iran-Iraq War have long departed, the seeds sowed by the conflict continue to have rippling effects for the region today. With Iranian soft power at unprecedented levels, what will the future hold for Iraq?