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Yemen was already suffering from serious air and water pollution due to the country's war. Israel's recent airstrikes have worsened the situation.
The Houthi rebels' health ministry said 'bacterial contamination' had been detected in the injections administered to the children, who were being treated for leukaemia.
Human rights organisations have called for an investigation into the deaths of 10 child cancer patients in Yemen after they were given expired medicine.
The effects of seven years of brutal war have left Yemen's mental healthcare services overwhelmed.
The nearly eight-hour operation which required 25 surgeons and technical advisers was performed in July.