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Syria's former Al-Qaeda affiliate Hayat Tahrir al-Sham (HTS) controls most of Idlib province as well as parts of neighbouring Aleppo, Hama and Latakia provinces.
Regime forces captured a village in opposition-held northern Hama province on Wednesday, while sustaining 15 casualties. Refugees are fleeing the city of Jisr al-Shughour following a massacre on Tuesday.
Syrian rebels say they have killed 30 regime fighters as the Assad forces captured two villages in northern Hama province and targeted a Turkish observation post.
Syrian regime aircraft carried out 20 airstrikes on opposition-held towns in Idlib province while attempting to advance further in northern Hama province amid an exacerbating humanitarian crisis.
The Syrian regime has captured the strategic town of Kafr Nabudah in northern Hama province, continuing its week-long offensive in the area. Thousands of civilians have fled.
Syria's military and Russia carried out more than 100 air raids in Idlib, Hama and Aleppo provinces, the Syrian Observatory for Human Rights said.
Rifaat al-Assad, dubbed the 'Butcher of Hama' for allegedly commanding troops that put down an uprising in Syria in 1982, has been under investigation in France since 2014.
Syrian rebels arrested 55 people in Hama and Idlib province over suspected collaboration with the regime.
Dr. Aziz Esber, director of the Center for Scientific Research in Masyaf was killed in an attack in Hama province near the town of Masyaf.
Scores of Syrian Faylaq al-Rahman rebels are arriving in Hama, after being evacuated from Eastern Ghouta's Arbin, leaving only one town under rebel control in the besieged Damascus enclave.