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Three children were among the dead as Syrian regime forces bombarded the opposition-held Idlib province.
Russian airstrikes destroyed the main water plant in Maarat al-Numan on Sunday as recently displaced refugees in the opposition-held town are unable to meet their basic needs.
Thirteen civilians were killed Friday by Syrian regime and Russian airstrikes, which for the first time struck the provincial capital of Idlib.
IS targeted the regime-controlled Taim oil field in Deir az-Zour with suicide bombings, shelling and machine gun fire, killing at least 17 Syrian regime forces.
Two rescuers were among nine civilians killed in Russian and regime airstrikes in northwest Syria, in the latest attack against relief workers in the region.
Two days of heavy airstrikes by Syria's regime and its ally Russia in northwestern Syria killed at least 22 civilians, a monitor said on Thursday.
Rocket fire has killed 12 civilians and wounded 15 others in a regime-held village in northwestern Syria.
Assad's deadly campaign against civilians in Idlib looks set to continue as a peace agreement brokered on Wednesday was breached just hours later.
Russia and Turkey have agreed on a complete ceasefire in Syria's Idlib province between Syrian regime forces and rebels.
Hundreds of mourners attended the burial of a Syrian goalkeeper who became an icon of the Syrian revolution after he died of wounds sustained in battle against regime forces.