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Heavy fighting was witnessed on the front lines between rebel and regime forces in Idlib on Friday.
The Syrian regime and Russia have upped their bombardment of the region since late April, killing more than 400 civilians.
The Syrian Observatory for Human Rights says that 45 combatants have been killed in clashes after rebels tried to retake territory recently lost to the regime.
Airstrikes and shelling killed 28 people in Idlib as Turkey accused Russia of making 'excuses' not to implement Thursday's ceasefire deal.
Syrian state media said the country responded to Israeli strikes on the country on Wednesday.
Syrian rebels said that they had launched a counter-offensive on Thursday to retake villages captured by the regime since April. The regime has recently captured 18 villages in northwestern Syria.
Bombings by Syrian regime forces damaged two schools and a health facility in the rebels' last stronghold in the northwest, activists said on Thursday.
The Syrian regime and its ally Russia are engaged in a 'deliberate and systematic assault' on hospitals in the country's northwest, Amnesty International said on Friday.
Twelve have been killed, including six in Aleppo as the Assad regime continues its deadly assault on provinces in the country's northwest.
Sources close to the opposition negotiating team say that Russia’s current deadly bombardment of Idlib is a response to the opposition’s rejection of a 'land-grab' proposal