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Several Arab countries are among those hit hardest by bombings, kidnappings and shootings, a global think tank reported.
Feature: Unable to get visas to Turkey, Palestinians from Syria residing in Lebanon are being forced to return to the war-torn country in order to reach the gate-way to Europe.
Analysis: Military developments in northern Syria, most recently rebels' advances against IS in Aleppo with US and Turkish air support, could be first step towards establishing a "safe zone" there.
Feature: Children at Iraq's Kawergosk refugee camp have already lost so much and now they are losing their teachers, as many leave for Europe in search of a better life.
Analysis: The WHO is vaccinating people against the devastating water-borne disease, as it spreads across Iraq and northern Syria.
Analysis: Despite mounting civilian losses, as Russian war planes join the violent melee with raids on rebel and Islamic State group targets, the opposition's resolve appears only to be solidifying.
Analysis: With little to show for a year of air raids against the Islamic State group, coalition forces are set to increase their efforts.
Social media posts and videos from Islamic State extremists have allowed analysts to pinpoint their movements in Iraq and Syria, highlighting the group's increasing push towards government strongholds.
Analysis: Despite non-attendance of Syrian National Coalition, delegates have stated their support for a political solution to Syria's rampaging violence.
Militants are reportedly within 500 metres of Hasakah, north east Syria, amid heavy regime bombing that has forced more than 3,000 people over the border into Turkey.